NIV failure in respiratory failure: an analysis

Abstract Objective Noninvasive ventilation (NIV) has become an increasingly accepted mode of treatment for acute respiratory failure. Concept NIV revolutionized the failure in terms spectrum diseases that can be successfully managed, locations its application, and achievable goals. The study was aimed at analyzing various aspects Material methods In this prospective observational study, all patients who underwent therapy from September 2019 to June 2020 were recruited. clinical, radiological, laboratory other relevant data satisfying inclusion criteria collected analyzed using appropriate statistical tools. Results Out 96 applications, 19 (19.8%) failed application form intubation 12 in-hospital mortality 8 (8.3% total group). A 73.7% (14/19) had early failure, 26.3% (5/19) late median length hospital stay significantly higher group compared success ( p < 0.001). outcomes like rate, mortality, did not have any difference between type 1 2 ARF > 0.05). found with pneumonia ILD group, respectively baseline rate more than 37 per minute, pH 7.28, pCO2 77 mm Hg measured 1–2 h after initiation, hyponatremia, prior history identified as independent predictors Using a modality secondary chances Conclusion Though is preferred initial tool management it should judiciously used when risk factors are present. Early escalation or upfront use invasive mechanical considered such scenario prevent undue morbidity patients. Main points • Key point behind successful expansion capacity achieve same clinical avoidance complications associated it. Delay identifying likely fail cause delay intubation; lead deterioration increased mortality. Predictors deciphered following low pH, hypercapnia despite NIV.